{"ID":"hsa04061","Term_Description":"Viral protein interaction with cytokine and cytokine receptor","Fold_Enrichment":11.25846,"occurrence":10,"support":0.00553,"lowest_p":1.25604e-17,"highest_p":1.25604e-17,"Up_regulated":"CCL7, CCL8, CCL2, CCL20, CXCL1, CXCL2, CXCL3, CXCL8, CXCL12, IL6, IL24","Down_regulated":"CCR10"}
{"ID":"hsa04062","Term_Description":"Chemokine signaling pathway","Fold_Enrichment":5.21944,"occurrence":10,"support":0.00553,"lowest_p":3.45867e-15,"highest_p":3.45867e-15,"Up_regulated":"CXCL1, CXCL2, CXCL3, CXCL8, CCL2, CCL7, CCL8, CCL20, CXCL12","Down_regulated":"CCR10, ADCY4"}
{"ID":"hsa04060","Term_Description":"Cytokine-cytokine receptor interaction","Fold_Enrichment":5.7672,"occurrence":10,"support":0.00553,"lowest_p":1.30875e-13,"highest_p":1.30875e-13,"Up_regulated":"IL24, CSF3, IL6, CXCL12, CXCL8, CXCL1, CXCL2, CXCL3, CCL7, CCL2, CCL8, CCL20","Down_regulated":"TNFRSF18, TNFSF9, TNFSF8, IFNGR2, IFNAR2, PRLR, CCR10"}
{"ID":"hsa05323","Term_Description":"Rheumatoid arthritis","Fold_Enrichment":10.19284,"occurrence":10,"support":0.00553,"lowest_p":9.57188e-09,"highest_p":9.57188e-09,"Up_regulated":"IL6, MMP1, CXCL12, CXCL8, CXCL1, CXCL2, CXCL3, CCL20, FOS, CCL2","Down_regulated":""}
{"ID":"hsa04657","Term_Description":"IL-17 signaling pathway","Fold_Enrichment":10.8117,"occurrence":10,"support":0.00553,"lowest_p":1.15295e-08,"highest_p":1.15295e-08,"Up_regulated":"IL6, FOS, CXCL1, CXCL2, CXCL3, CCL2, CCL7, CCL20, CXCL8, MMP1, CSF3","Down_regulated":""}
{"ID":"hsa04330","Term_Description":"Notch signaling pathway","Fold_Enrichment":4.19807,"occurrence":10,"support":0.00553,"lowest_p":2.87487e-06,"highest_p":2.87487e-06,"Up_regulated":"TLE3, DTX4","Down_regulated":"PSEN1"}
{"ID":"hsa04668","Term_Description":"TNF signaling pathway","Fold_Enrichment":5.72212,"occurrence":10,"support":0.00553,"lowest_p":8.57908e-06,"highest_p":8.57908e-06,"Up_regulated":"FOS, CCL2, CCL20, CXCL1, CXCL2, CXCL3, IL6","Down_regulated":""}
{"ID":"hsa03020","Term_Description":"RNA polymerase","Fold_Enrichment":6.60496,"occurrence":10,"support":0.01658,"lowest_p":0.00005,"highest_p":0.00005,"Up_regulated":"POLR3B","Down_regulated":"POLR2A"}
{"ID":"hsa04820","Term_Description":"Cytoskeleton in muscle cells","Fold_Enrichment":3.10092,"occurrence":1,"support":0.00541,"lowest_p":0.00009,"highest_p":0.00009,"Up_regulated":"DCN, THBS1, THBS2, AMPD2, SNTB1","Down_regulated":"AGRN, AMPD3, SPTAN1"}
{"ID":"hsa03410","Term_Description":"Base excision repair","Fold_Enrichment":5.89729,"occurrence":10,"support":0.03297,"lowest_p":0.00032,"highest_p":0.00032,"Up_regulated":"APEX1, PARP1, TDP1","Down_regulated":""}
{"ID":"hsa04512","Term_Description":"ECM-receptor interaction","Fold_Enrichment":3.93153,"occurrence":1,"support":0.00541,"lowest_p":0.00057,"highest_p":0.00057,"Up_regulated":"IBSP, THBS1, THBS2","Down_regulated":"AGRN"}
{"ID":"hsa05412","Term_Description":"Arrhythmogenic right ventricular cardiomyopathy","Fold_Enrichment":3.13527,"occurrence":10,"support":0.01105,"lowest_p":0.00075,"highest_p":0.00075,"Up_regulated":"ATP2A3, GJA1, SNTB1","Down_regulated":""}
{"ID":"hsa04064","Term_Description":"NF-kappa B signaling pathway","Fold_Enrichment":8.44385,"occurrence":10,"support":0.01105,"lowest_p":0.00104,"highest_p":0.00104,"Up_regulated":"CARD14, CXCL8, CXCL12, PARP1, CXCL1, CXCL2, CXCL3","Down_regulated":"BCL2A1, TRIM25"}
{"ID":"hsa04972","Term_Description":"Pancreatic secretion","Fold_Enrichment":3.55106,"occurrence":10,"support":0.00553,"lowest_p":0.00262,"highest_p":0.00262,"Up_regulated":"ATP2A3, RAB27B","Down_regulated":"ATP2B1, ADCY4"}
{"ID":"hsa04210","Term_Description":"Apoptosis","Fold_Enrichment":3.38369,"occurrence":10,"support":0.0221,"lowest_p":0.00279,"highest_p":0.00279,"Up_regulated":"PARP1, FOS","Down_regulated":"SPTAN1, PMAIP1, BCL2A1"}
{"ID":"hsa04915","Term_Description":"Estrogen signaling pathway","Fold_Enrichment":1.99747,"occurrence":10,"support":0.00553,"lowest_p":0.00293,"highest_p":0.00293,"Up_regulated":"FOS, HSPA8","Down_regulated":"ADCY4"}
{"ID":"hsa05162","Term_Description":"Measles","Fold_Enrichment":2.64199,"occurrence":10,"support":0.01105,"lowest_p":0.003,"highest_p":0.003,"Up_regulated":"HSPA8, IL6, FOS","Down_regulated":"IFNAR2"}
{"ID":"hsa04141","Term_Description":"Protein processing in endoplasmic reticulum","Fold_Enrichment":2.26197,"occurrence":10,"support":0.01105,"lowest_p":0.00478,"highest_p":0.00478,"Up_regulated":"HSPA5, HSPA8, HERPUD1, SEC13","Down_regulated":""}
{"ID":"hsa04621","Term_Description":"NOD-like receptor signaling pathway","Fold_Enrichment":4.20698,"occurrence":10,"support":0.01105,"lowest_p":0.00594,"highest_p":0.00594,"Up_regulated":"NAMPT, IL6, CXCL8, CXCL1, CXCL2, CXCL3, CCL2","Down_regulated":"IFNAR2"}
{"ID":"hsa03040","Term_Description":"Spliceosome","Fold_Enrichment":2.60038,"occurrence":10,"support":0.00553,"lowest_p":0.00669,"highest_p":0.00669,"Up_regulated":"HNRNPA1L2, RBMX, HNRNPA1, HSPA8","Down_regulated":""}
{"ID":"hsa05417","Term_Description":"Lipid and atherosclerosis","Fold_Enrichment":5.16013,"occurrence":10,"support":0.02198,"lowest_p":0.00682,"highest_p":0.01084,"Up_regulated":"MMP1, FOS, CCL2, CXCL8, IL6, HSPA5, CXCL1, CXCL2, CXCL3, HSPA8","Down_regulated":"PPP3CC, POU2F2"}
{"ID":"hsa04928","Term_Description":"Parathyroid hormone synthesis, secretion and action","Fold_Enrichment":3.93153,"occurrence":10,"support":0.00553,"lowest_p":0.00688,"highest_p":0.00688,"Up_regulated":"PDE4D, CYP24A1, FOS, EGR1","Down_regulated":"ADCY4"}
{"ID":"hsa04110","Term_Description":"Cell cycle","Fold_Enrichment":1.70818,"occurrence":10,"support":0.01105,"lowest_p":0.00699,"highest_p":0.00699,"Up_regulated":"MCM6, CDC6, PDS5B","Down_regulated":""}
{"ID":"hsa04261","Term_Description":"Adrenergic signaling in cardiomyocytes","Fold_Enrichment":1.8484,"occurrence":10,"support":0.00553,"lowest_p":0.00785,"highest_p":0.00785,"Up_regulated":"ATP2A3","Down_regulated":"ADCY4, ATP2B1"}
{"ID":"hsa04022","Term_Description":"cGMP-PKG signaling pathway","Fold_Enrichment":2.80823,"occurrence":10,"support":0.00553,"lowest_p":0.01036,"highest_p":0.01036,"Up_regulated":"ATP2A3, SLC25A5","Down_regulated":"PPP3CC, ATP2B1, ADCY4"}
{"ID":"hsa03060","Term_Description":"Protein export","Fold_Enrichment":2.94864,"occurrence":1,"support":0.00568,"lowest_p":0.01367,"highest_p":0.01367,"Up_regulated":"HSPA5","Down_regulated":""}
{"ID":"hsa05418","Term_Description":"Fluid shear stress and atherosclerosis","Fold_Enrichment":1.87641,"occurrence":10,"support":0.00553,"lowest_p":0.01767,"highest_p":0.01767,"Up_regulated":"FOS, CCL2, DUSP1","Down_regulated":""}
{"ID":"hsa05020","Term_Description":"Prion disease","Fold_Enrichment":2.51276,"occurrence":10,"support":0.00553,"lowest_p":0.02189,"highest_p":0.02189,"Up_regulated":"EGR1, IL6, HSPA8, C9, HSPA5, SLC25A5","Down_regulated":"PPP3CC"}
{"ID":"hsa04010","Term_Description":"MAPK signaling pathway","Fold_Enrichment":2.18915,"occurrence":10,"support":0.00553,"lowest_p":0.02798,"highest_p":0.02798,"Up_regulated":"DUSP1, MRAS, MAP3K12, HSPA8, FOS, AREG","Down_regulated":"PPP3CC"}
{"ID":"hsa04024","Term_Description":"cAMP signaling pathway","Fold_Enrichment":2.40472,"occurrence":10,"support":0.00553,"lowest_p":0.02828,"highest_p":0.02828,"Up_regulated":"ATP2A3, PDE4D, FOS","Down_regulated":"ADCY4, ATP2B1, ADCY10"}
{"ID":"hsa00860","Term_Description":"Porphyrin metabolism","Fold_Enrichment":8.69074,"occurrence":10,"support":0.00553,"lowest_p":0.0326,"highest_p":0.0326,"Up_regulated":"CPOX, FXN, FTH1, HMBS","Down_regulated":""}
{"ID":"hsa05134","Term_Description":"Legionellosis","Fold_Enrichment":9.90745,"occurrence":10,"support":0.01648,"lowest_p":0.03314,"highest_p":0.04413,"Up_regulated":"HSPA8, IL6, CXCL8, CXCL1, CXCL2, CXCL3","Down_regulated":""}
{"ID":"hsa04144","Term_Description":"Endocytosis","Fold_Enrichment":1.12075,"occurrence":10,"support":0.00553,"lowest_p":0.03484,"highest_p":0.03484,"Up_regulated":"HSPA8, DAB2, EHD3","Down_regulated":""}
{"ID":"hsa04216","Term_Description":"Ferroptosis","Fold_Enrichment":6.19215,"occurrence":10,"support":0.00553,"lowest_p":0.03615,"highest_p":0.03615,"Up_regulated":"PCBP2, FTH1, ACSL4","Down_regulated":""}
{"ID":"hsa04213","Term_Description":"Longevity regulating pathway - multiple species","Fold_Enrichment":3.05785,"occurrence":9,"support":0.00549,"lowest_p":0.03869,"highest_p":0.03869,"Up_regulated":"HSPA8","Down_regulated":"ADCY4"}
{"ID":"hsa04020","Term_Description":"Calcium signaling pathway","Fold_Enrichment":1.78706,"occurrence":10,"support":0.00553,"lowest_p":0.03971,"highest_p":0.03971,"Up_regulated":"SLC25A5, ATP2A3","Down_regulated":"PPP3CC, ADCY4, ATP2B1"}
{"ID":"hsa04672","Term_Description":"Intestinal immune network for IgA production","Fold_Enrichment":8.2562,"occurrence":10,"support":0.00553,"lowest_p":0.04514,"highest_p":0.04514,"Up_regulated":"IL6, CXCL12","Down_regulated":"CCR10, ICOSLG"}
{"ID":"hsa05219","Term_Description":"Bladder cancer","Fold_Enrichment":6.51806,"occurrence":10,"support":0.00553,"lowest_p":0.04969,"highest_p":0.04969,"Up_regulated":"MMP1, CXCL8, THBS1","Down_regulated":""}